Fig 2: Effect of Oct-LMSG on type I collagen mRNA transcription in L929 fibroblasts. The mRNA levels of Col1A1 and Col1A2 were determined by reverse transcription-quantitative PCR assay after treatment with either Oct-LMSG (100 µg/ml) or TGF-β (10 ng/ml) for 6, 12 and 24 h relative to GAPDH. Values are expressed as the mean ± standard error of the mean of three independent experiments. *P<0.05 vs. control. Oct-LMSG, low molecular weight sulfated galactan added with octanoyl moiety; Col1A1, collagen type I α1 chain.